For more than three decades, the UW Medical Physics Cyclotron Group has been providing radionuclides and radiotracers to it colleagues on campus.
We are able to provide the standard PET isotopes, 18F, 11C, and 13N on a daily basis.
Isotope | Form | Halflife | Typical Specific Activty (Ci/umol@EOS**) |
18F | 18F- | 110 min. | 10->50 |
11C | 11CH3I/11CH3OTf | 20 min. | 10-25 |
13N | 13NH3 | 10 min. | – |
We also provide local collaborators unconventional isotopes upon request.
Isotope | Form | Halflife | Typical Effective Specific Activty* (Ci/umol@EOB**) |
44Sc | 44ScCl3 | 3.97 hours | 1-8 (DOTA) |
51Mn | 51MnCl2 | 46 min. | N.C.A. |
61Cu | 61CuCl2 | 3.3 hours | 1-2 (DOTA) |
55/58Co | 55/58CoCl2 | 17/70 hours | >1 (DOTA) |
80mBr | Na76/77Br | 4.4 hours | N.C.A. |
For the last decade, the cyclotron group has been distributing radionuclides to colleagues for basic research locally and at several dozen laboratories across the country. Copper-64, zirconium-89, and yttrium-86 are produced and shipped Mondays by overnight Fed Ex Express for delivery by 10:30am Tuesday mornings. Arsenic-72, bromine-76/77, manganese-52 and others are available on request. We are also members of the U.S. Department of Energy’s University Isotope Network (UIN); requests for Y-86, Br-77, and Mn-52 can be directed to isotopes.gov.
Isotope | Form | Halflife | Typical AMA (Ci/umol@EOB**) |
52Mn | 52MnCl2 | 5.6 days | ~0.5 (DOTA) |
64Cu | 64CuCl2 | 12.7 hours | 1- >15 (NOTA) |
86Y | 86YCl3 | 14.7 hours | 2 (DOTA, DTPA) |
72As | 72As(v)OCl3 | 26 hours | N.C.A. (70,74As also available) |
76/77Br | Na76/77Br | 16.2/57 hours | N.C.A. |
89Zr | 89Zr Oxalate | 78 hours | 1-3 (DFO) |
Details concerning ordering and other novel radionuclides above or not listed here are available by request to cyclotron.gang@gmail.com.
* The ISRS-defined quantity “apparent molar activity” is measured for many radiometals with a specified complexing ligand (e.g., DOTA or NOTA). The complexing ligand is shown parenthetically, and measurement are made using titrated solutions of the ligand and radio-TLC.
** EOB = End of Bombardment; EOS = End of Synthesis.