UW-Madison Cyclotron Lab
Please reach out to us at cyclotron.gang@gmail.com

Research

Our interest is in the production and application of radionuclides to research questions in medical and fundamental science. We are eager to see our work applied to the diagnosis and treatment of disease, to improving materials used in future reactor designs, understanding migration of toxic molecules in geological samples, or to shoring up holes in nuclear databases. All of our work starts with one of our two cyclotrons, which we use to make the radioactive materials we and others need for application-oriented research. A sampling of recent publications is included below. Please do not hesitate to contact Jon if you have an interest or would like to discuss further.

  1. Radchenko V, Kostelnik T I, Olson A P, Grundmane A, Ellison P A, Myernich J, Chen S, Marinova A, Randhawa P, Karaivanov D, Aluicio-Sarduy E, Barnhart T E, Orvig C, Ramogida C F, Hoehr C, Filosofov D, Engle J W (2023). Production and radiochemistry of Antimony-120m: Efforts toward auger electron therapy with 119 Nuclear Medicine and Biology, accepted. DOI: 10.1016/j.nucmedbio.2023.108352
  2. Becker K V, Aluicio-Sarduy E, Bradshaw T, Hurley S A, Olson A P, Barrett K E, Batterton J, Ellison P A, Barnhart T E, Pirasteh A, Engle J W (2023). Cyclotron production of 43Sc and 44gSc from enriched 42CaO, 43CaO, and 44CaO targets. Frontiers in Chemistry, 11, 1. DOI: 10.3389/fchem.2023.1167783.
  3. Kretowicz M N, Barrett K E, Barnhart T E, Engle J W (2023). Recycling of 52Cr electroplated targets for 52gMn production. Applied Radiation Isotopes, accepted. DOI: 10.2139/ssrn.4355034
  4. Lin W, Aluicio-Sarduy E, Houson H A, Barnhart T E, Tekin V, Jeffery J J, Weichmann A M, Barrett K E, Lapi S E, Engle J W (2023). Theranostic cobalt-55/58m for neurotensin receptor-mediated therapy in vivo: a pilot study with dosimetry. Nuclear Medicine Biology, 118-119, 108329. DOI: 10.1016/j.nucmedbio.2023.108329
  5. Aluicio-Sarduy E, Barnhart T E, Weichert J, Hernandez R, Engle J W (2020). Cyclotron produced 132La as a PET imaging surrogate of therapeutic 225Ac. Journal of Nuclear Medicine, 62 (7), 1012-1015. DOI: 10.2967/jnumed.120.255794.