Todd E. Barnhart

Position title: Cyclotron Director

Email: tebarnhart@wisc.edu

Phone: +1 608 263 5805

Address:
B1303 WIMR Cyclotron Laboratory
1111 Highland Avenue
Madison, WI 53705

Publications

  1. Aluicio-Sarduy, E., Ellison, P. A., Barnhart, T. E., Cai, W., Nickles, R. J., Engle, J. W. PET Radiometals for Antibody Labeling. J Labelled Comp Radiopharm. 2018
  2. Betthauser, T. J., Ellison, P. A., Murali, D., Lao, P. J., Barnhart, T. E., Furumoto, S., Okamura, N., Johnson, S. C., Engle, J. W., Nickles, R. J., Christian, B. T. Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau. Appl Radiat Isot. 2017 130:230-237
  3. Valdovinos, H. F., Hernandez, R., Graves, S., Ellison, P. A., Barnhart, T. E., Theuer, C. P., Engle, J. W., Cai, W., Nickles, R. J. Cyclotron production and radiochemical separation of 55Co and 58mCo from 54Fe, 58Ni and 57Fe targets. Appl Radiat Isot. 2017 130:90-101
  4. Lao, P. J., Handen, B. L., Betthauser, T. J., Mihaila, I., Hartley, S. L., Cohen, A. D., Tudorascu, D. L., Bulova, P. D., Lopresti, B. J., Tumuluru, R. V., Murali, D., Mathis, C. A., Barnhart, T. E., Stone, C. K., Price, J. C., Devenny, D. A., Mailick, M. R., Klunk, W. E., Johnson, S. C., Christian, B. T. Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population. Alzheimers Dement. 2017 9:1-9
  5. Graves, S. A,, Hernandez, R., Valdovinos, H. F., Ellison, P. A., Engle, J. W., Barnhart, T. E., Cai, W., Nickles, R. J. Preparation and in vivo characterization of 51MnCl2 as PET tracer of Ca2+ channel-mediated transport. Sci Rep. 2017 7(1):3033
  6. Hernandez, R., Graves, S. A., Gregg, T., Van Deusen, H. R., Fenske, R. J., Wienkes, H. N., England, C. G., Valdovinos, H. F., Jeffery, J. J., Barnhart, T. E., Severin, G. W., Nickles, R. J., Kimple, M. E., Merrins, M. J., Cai, W. Radiomanganese PET Detects Changes in Functional β-cell Mass in Mouse Models of Diabetes. Diabetes. 2017 66(8):2163-2174
  7. Chen F, Valdovinos HF, Hernandez R, Goel S, Barnhart TE, Cai W. Intrinsic radiolabeling of Titanium-45 using mesoporous silica nanoparticles. Acta Pharmacol Sin. 2017 38(6):907-913
  8. Ellison, P. A., Chen, F., Goel, S., Barnhart, T. E., Nickles, R. J., DeJesus, O. T., Cai, W. Intrinsic and Stable Conjugation of Thiolated Mesoporous Silica Nanoparticles with Radioarsenic. ACS Appl Mater Interfaces. 2017, 9(8): 6772-6781
  9. Ellison, P. A., Valdovinos, H. F., Graves, S. A., Barnhart, T. E., Nickles, R. J. Spot-welding solid targets for high current cyclotron irradiation. Appl Radiat Isot. 2016 118:350-353
  10. Graves, S. A., Ellison, P. A., Barnhart, T. E., Valdovinos, H. F., Birnbaumb, E. R., Nortier, F. M., Nickles, R. J., Engle, J. W. Nuclear excitation functions of proton-induced reactions (Ep = 35–90 MeV) from Fe, Cu, and Al. Nucl. Instr. Methods B, 2016 386: 44–53
  11. Croce, M. P., Rabin, M. W., Mocko, V., Kunde, G. J. Birnbaum, E. R. Bond, E. M., Engle, J. W., Hoover, A. S., Nortier, F. M., Pollington, A. D., Taylor, W. A., Weisse-Bernstein, N. R., Wolfsberg, L. E., Hays-Wehle, J. P., Schmidt, D. R., Swetz, D. S., Ullom, J. N., Barnhart, T. E., Nickles, R. J. Development of Holmium-163 Electron-Capture Spectroscopy with Transition-Edge Sensors. J Low Temp Phy 2016 184(3-4): 958-968
  12. Ellison, P.A., Barnhart, T. E., Chen, F., Hong, H., Zhang, Y., Theuer, C. P., Cai, W.B., Nickles, R. J., DeJesus, OT. High Yield Production and Radiochemical Isolation of Isotopically Pure Arsenic-72 and Novel Radioarsenic Labeling Strategies for the Development of Theranostic Radiopharmaceuticals. Bioconjug Chem. 2016 27(1): 179-188
  13. Mocko, V., Taylor, W. A., Nortier, F. M. Engle, J. W., Barnhart, T. E., Nickles, R. J., Pollington, A. D., Kunde, G. J.,; Rabin, M. W., Birnbaum, E. R. Isolation of Ho-163 from dysprosium target material by HPLC for neutrino mass measurements. Radiochimica Acta. 2015 103(8): 577-585
  14. Graves, S. A , Hernandez, R., Fonslet, J., England, C. G., Valdovinos, H. F., Ellison, P. A., Barnhart, T. E, Elema, D. R., Theuer, C. P., Cai, W., Nickles, R. J., Severin, G. W. Novel Preparation Methods of 52Mn for ImmunoPET Imaging. Bioconjug Chem. 2015 26(10):2118-24
  15. Lewis, C. M., Graves, S. A., Hernandez, R., Valdovinos, H. F., Barnhart, T. E., Cai, W., Meyerand, M. E., Nickles, R. J., Suzuki, M. 52Mn Production for PET/MRI Tracking Of Human Stem Cells Expressing Divalent Metal Transporter 1 (DMT1). Theranostics. 2015 5(3):227-39
  16. Severin, G. W., Engle, J. W., Valdovinos, H. F., Barnhart, T. E., Nickles, R. J. Cyclotron produced 44gSc from natural calcium. Appl Rad Isot 2012; 70(8):1526-1530
  17. Engle, J. W., Hong, H., Zhang, Y., Valdovinos, H. F., Myklejord, D. V., Barnhart, T. E., Theuer, C. P., Nickles, R. J., Cai, W. Positron emission tomography imaging of tumor angiogenesis with a 66Ga-labeled monoclonal antibody. Mol Pham 2012; 9(5):1441-1448
  18. Engle, J. W., Lopez-Rodriguez, V., Gaspar-Carcamo, R. E., Valdovinos, H. F., Valle-Gonzalez, M., Trejo-Ballado, F., Severin, G. W., Barnhart, T. E., Nickles, R. J., Avila-Rodriguez, M. A. Very high specific activity 66/68Ga from zinc targets for PET. Appl Radiat Isot 2012; 70(8):1792-1796
  19. Engle, J. W., Severin, G. W., Barnhart, T. E., Knutson, L. D., Nickles, R. J. Cross sections of the 36Ar(d,)34mCl, 40Ar(d,)38Cl, and 40Ar(d,p)41Ar nuclear reactions below 8.4 MeV. Appl Radiat Isot 2012; 70(2):355-359
  20. Engle, J. W., Barnhart, T. E., Severin, G. W., Nickles, R. J. The unrealized potential of 34mCl for radiopharmaceutical research with PET. Current Radiopharm 2011; 4(2):102-108